Synthesis of New N-Phthalimide Substituted Tricyclic Imide Containing Isoxazoline and Bispiro Functional Group as Possible Anti-cancer Agents

Synthesis of some new isoxazoline derivatives as possible anti-Candida agents.

The isoxazolines have been reported to possess a variety of significant and diverse pharmacological activities such as antifungal (1, 2), anti-HIV (3), anti-bacterial (4), caspase inhibitory (5), antimuscarinic (6), anti-inflammatory (7), anticancer (8) and anti-depressant (9) activity. On the other hand, the object of antifungal drug discovery has become a subject of greater challenge due to i...

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Synthesis of N-arylmethyl Substituted Indole Derivatives as New Antiplatelet Aggregation Agents

A number of N-arylmethyl substituted indole derivatives have been synthesized and their effectiveness against ADP and arachidonic acid induced platelet aggregation in human plasma was determined. The desired compounds were synthesized by reacting the appropriate aniline derivative with isatin (or substituted isatin) to form the corresponding imine structures. The so formed compound was then act...

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Synthesis of N-arylmethyl Substituted Indole Derivatives as New Antiplatelet Aggregation Agents

A number of N-arylmethyl substituted indole derivatives have been synthesized and their effectiveness against ADP and arachidonic acid induced platelet aggregation in human plasma was determined. The desired compounds were synthesized by reacting the appropriate aniline derivative with isatin (or substituted isatin) to form the corresponding imine structures. The so formed compound was then act...

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Synthesis of some new tetrahydropyrimidine derivatives as possible antibacterial agents

Heterocyclic compounds containing a pyrimidine nucleus are of special interests due to their applications in medicinal chemistry as they are the basic skeleton of several bioactive compounds such as antifungal, antibacterial, antitumor and antitubercular. As a part of our research in the synthesis of pyrimidine derivatives containing biological activities, some new tetrahydropyrimidine derivati...

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Synthesis of some new tetrahydropyrimidine derivatives as possible antibacterial agents

Heterocyclic compounds containing a pyrimidine nucleus are of special interests due to their applications in medicinal chemistry as they are the basic skeleton of several bioactive compounds such as antifungal, antibacterial, antitumor and antitubercular. As a part of our research in the synthesis of pyrimidine derivatives containing biological activities, some new tetrahydropyrimidine derivati...

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Synthesis of New N-Phthalimide Substituted Tricyclic Imide Containing Isoxazoline and Bispiro Functional Group as Possible Anti-cancer Agents

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Synthesis of some new isoxazoline derivatives as possible anti-Candida agents.

Synthesis of N-arylmethyl Substituted Indole Derivatives as New Antiplatelet Aggregation Agents

Synthesis of N-arylmethyl Substituted Indole Derivatives as New Antiplatelet Aggregation Agents

Synthesis of some new tetrahydropyrimidine derivatives as possible antibacterial agents

Synthesis of some new tetrahydropyrimidine derivatives as possible antibacterial agents

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